Xiong, WS et al. Protective effects of gypenosides on experimental myocardial infarction. Zhongguo Yao Li Xue Bao. 1990 Sept,11.
Dr. Xiong studied the effects of Jioagulan on myocardial infarction. He found in an animal study that the gypenosides in Jiaogulan reduced the size of myocardial infarctions and the free fatty acids in the blood serum. He suggests that the effect is related to the strong anti-oxidative properties of Jiaogulan.
Tanner, MA et al. The Direct Release of Nitric Oxide by Gypenosides Derived from the Herb Gynostemma pentaphyllum. Nitric Oxide Oct. 1999.
Dr. Tanner and his team from Vanderbilt University Medical Center investigated the vasorelaxation effects of Jiaogulan. They found that gypenosides from Jiaogulan caused the lining of blood vessels to release nitric oxide.. The nitric oxide release relaxed the blood vessels resulting in more efficient blood flow.
Tan H et al. Antithrombotic effect of Gynostemma pentaphyllum Zhongguo Zhong Xi Yi Jie He Za Zhi. 1993 May;13.
Thrombosis is another term for blood clotting. Clots can lead to heart attack and stroke. Researchers in China found that a water extract from Jiaogulan “could inhibit significantly the platelet aggregation induced by ADP and compound agonists (P < 0.05), accelerate obviously the disaggregation (P < 0.05) and inhibit effectively the experimental thrombosis (P < 0.05). The delayed effects of GP on KPTT, PT, TT, AT, RVV-RT, RVV-CT suggested that this drug could decrease the activity of multiple coagulation factors. And it showed that GP could accelerate the erythrocyte electrophoresis rate. This study revealed that GP is an antithrombotic agent affecting the links of thrombotic chain.”
Chen, L.F., et al. Comparisons of the effects of Gypenosides and ginsenosides on cardiac function and hemodynamics in dogs. Zhongguo Yaolixue Yu Dulixue Zazhi. China 1990
Dr. Chen and his team studied the effects of jiaogulan and ginseng on the cardiovascular efficiency of dogs. They found that the dogs that received Jiaogulan significantly lowered their systolic and diastolic blood pressure and decreased their total peripheral, brain and coronary blood vessel resistance. Ginseng was found to have a similar but less significant effect.