Li ChangJun; Wu XiaoLan; Lou XiaoJuan; Wu YaJun; Li Ang; Wang HaiYan. Protective effects of crude polysaccharide from Gynostemma pentaphyllum on swimming exercise-induced oxidative stress in rat. Journal Journal of Animal and Veterinary Advances 2012 Vol. 11 No. 10
In this study, the test subjects (rats) were fed Jiaogulan for 30 days and subjected to a swimming endurance test. Those subjects given Jiaogulan showed significantly longer swim times and, based on liver glycogen measurements after the swim, were likely to recover faster. This research suggests that Jiaogulan may be beneficial to athletes hoping to improve endurance and excercise recoevery.
Xiong, WS et al. Protective effects of gypenosides on experimental myocardial infarction. Zhongguo Yao Li Xue Bao. 1990 Sept,11.
Dr. Xiong studied the effects of Jioagulan on myocardial infarction. He found in an animal study that the gypenosides in Jiaogulan reduced the size of myocardial infarctions and the free fatty acids in the blood serum. He suggests that the effect is related to the strong anti-oxidative properties of Jiaogulan.
Tanner, MA et al. The Direct Release of Nitric Oxide by Gypenosides Derived from the Herb Gynostemma pentaphyllum. Nitric Oxide Oct. 1999.
Dr. Tanner and his team from Vanderbilt University Medical Center investigated the vasorelaxation effects of Jiaogulan. They found that gypenosides from Jiaogulan caused the lining of blood vessels to release nitric oxide.. The nitric oxide release relaxed the blood vessels resulting in more efficient blood flow.
Chen, L.F., et al. Comparisons of the effects of Gypenosides and ginsenosides on cardiac function and hemodynamics in dogs. Zhongguo Yaolixue Yu Dulixue Zazhi. China 1990
Dr. Chen and his team studied the effects of jiaogulan and ginseng on the cardiovascular efficiency of dogs. They found that the dogs that received Jiaogulan significantly lowered their systolic and diastolic blood pressure and decreased their total peripheral, brain and coronary blood vessel resistance. Ginseng was found to have a similar but less significant effect.
Zhou, Ying-Na et al. Effects of gypensosides-containing tonics on the pulmonary functions in exercise workloads. Journal of Guiyang Medical College. 1993
Researchers at the Guiyang Medical College in China conducted studies of 220 athletes and 30 average subjects using color DOPLER imaging. The study showed that just 30 minutes after receiving a dose of gypenosides, 100% of the test subjects showed positive effects. The effects measured included, increased stroke volume and cardiac output, decreased left ventricular end-systolic diameter and increased left ventricular end-diastolic diameter. The heart rate and blood pressure did not increase. This implies that Jiaogulan improved the efficiency of the pumping action of the heart such that the heart did not have to work as had to produce the same volume of blood flow.