Tanner, MA et al. The Direct Release of Nitric Oxide by Gypenosides Derived from the Herb Gynostemma pentaphyllum. Nitric Oxide Oct. 1999.
Dr. Tanner and his team from Vanderbilt University Medical Center investigated the vasorelaxation effects of Jiaogulan. They found that gypenosides from Jiaogulan caused the lining of blood vessels to release nitric oxide.. The nitric oxide release relaxed the blood vessels resulting in more efficient blood flow.