Jiaogulan has Potential Preventive Effects on Myocardial Infarction

Xiong, WS et al. Protective effects of gypenosides on experimental myocardial infarction. Zhongguo Yao Li Xue Bao. 1990 Sept,11.

Dr. Xiong studied the effects of Jioagulan on myocardial infarction. He found in an animal study that the gypenosides in Jiaogulan reduced the size of myocardial infarctions and the free fatty acids in the blood serum. He suggests that the effect is related to the strong anti-oxidative properties of Jiaogulan.

Jiaogulan Linked to Nitric Oxide Production in Blood Vessels

Tanner, MA et al. The Direct Release of Nitric Oxide by Gypenosides Derived from the Herb Gynostemma pentaphyllum. Nitric Oxide Oct. 1999.

Dr. Tanner and his team from Vanderbilt University Medical Center investigated the vasorelaxation effects of Jiaogulan. They found that gypenosides from Jiaogulan caused the lining of blood vessels to release nitric oxide.. The nitric oxide release relaxed the blood vessels resulting in more efficient blood flow.

Jiaogulan found to be an “anti-thrombotic agent.”

Tan H et al. Antithrombotic effect of Gynostemma pentaphyllum Zhongguo Zhong Xi Yi Jie He Za Zhi. 1993 May;13.

Thrombosis is another term for blood clotting. Clots can lead to heart attack and stroke. Researchers in China found that a water extract from Jiaogulan “could inhibit significantly the platelet aggregation induced by ADP and compound agonists (P < 0.05), accelerate obviously the disaggregation (P < 0.05) and inhibit effectively the experimental thrombosis (P < 0.05). The delayed effects of GP on KPTT, PT, TT, AT, RVV-RT, RVV-CT suggested that this drug could decrease the activity of multiple coagulation factors. And it showed that GP could accelerate the erythrocyte electrophoresis rate. This study revealed that GP is an antithrombotic agent affecting the links of thrombotic chain.”

Jiaogulan May Produce Higher Coronary Flow and Lower Heart Rate

Chen, L.F., et al. Comparisons of the effects of Gypenosides and ginsenosides on cardiac function and hemodynamics in dogs. Zhongguo Yaolixue Yu Dulixue Zazhi. China 1990

Dr. Chen and his team studied the effects of jiaogulan and ginseng on the cardiovascular efficiency of dogs. They found that the dogs that received Jiaogulan significantly lowered their systolic and diastolic blood pressure and decreased their total peripheral, brain and coronary blood vessel resistance. Ginseng was found to have a similar but less significant effect.

Jiaogulan Linked to More Efficient Cardio Function

Zhou, Ying-Na et al. Effects of gypensosides-containing tonics on the pulmonary functions in exercise workloads. Journal of Guiyang Medical College. 1993

Researchers at the Guiyang Medical College in China conducted studies of 220 athletes and 30 average subjects using color DOPLER imaging. The study showed that just 30 minutes after receiving a dose of gypenosides, 100% of the test subjects showed positive effects. The effects measured included, increased stroke volume and cardiac output, decreased left ventricular end-systolic diameter and increased left ventricular end-diastolic diameter. The heart rate and blood pressure did not increase. This implies that Jiaogulan improved the efficiency of the pumping action of the heart such that the heart did not have to work as had to produce the same volume of blood flow.

Jiaogulan Linked to Nitric Oxide Production in Blood Vessels!

Tanner, MA et al. The Direct Release of Nitric Oxide by Gypenosides Derived from the Herb Gynostemma pentaphyllum. Nitric Oxide Oct. 1999.

Dr. Tanner and his team from Vanderbilt University Medical Center investigated the vasorelaxation effects of Jiaogulan. They found that gypenosides from Jiaogulan caused the lining of blood vessels to release nitric oxide.. The nitric oxide release relaxed the blood vessels resulting in more efficient blood flow.

Nitric Oxide is Key to Lowering Blood Pressure

Achike, F.I., et al. Nitric oxide, human diseases and the herbal products that affect the nitric oxide signaling pathway. Clinical and Experimental Pharmacology and Physiology, September 2003.

Researchers in Canada and Malaysia teamed up to research the stimulation of Nitric Oxide production by various herbal products. Nitric Oxide is believed a key factor in in controlling blood pressure because when released by the surface cells of blood vessels it causes the vessels to relax thus reducing blood pressure. the researchers found Jiaogulan to be one of the most effective herbs available in stimulating this reaction.

Jiaogulan is 82% Effective in Lowering High Blood Pressure

Lu, G.H., etal. Comparative Study of the anti-hypertensive effects of Gymenosides, ginseng and Indapamide in patients with essential hyperetension. Guizhou Medical Journal. China 1996.

Dr. Lu and his team studied 233 patients with high blood pressure. 1/3 of the patients received and extract from Jiaogulan, 1/3 received a ginseng extract and 1/3 received a popular pharmaceutical drug for high blood pressure. After 3 months they found the pharmaceutical drug was the most effective with a 93% effectiveness rate. Jiaogulan was close behind, 82% effective in controlling the patients high blood pressure. Ginseng was a distant third at 46%.

Jiaogulan Scavenge Free Radicals and Fights Bacteria

Suhua Zhu, Chengxiang Fang, Shiqiao Zhu, Fang Peng, Luozhen Zhang, Chengpeng Fan, Inhibitory Effects of Gynostemma Pentaphyllum on the UV Induction of Bacteriophage 5 in Lysogenic Escherichia coli. Current Microbiology. Aug. 2001.

In this study at Wuhan University in China they examined the effect of Jiaogulan on the growth of bacteriophages (viruses that attack bacteria, e-coli and cholera are both examples). They found that Jiaogulan did inhibit the growth of the bactriophages. They also found through Magnetic Resonance Imaging that Jiaogulan was an effective scavenger of free radicals.

Jiaogulan Found to Increase SOD in Seniors an Average of 282%

Liu, Jialiu, et al. Effects of gypenosides-containing tonics on the serum SOD activity and MDA content in middle aged persons. Journal of Guiyang Medical College. 1994.

Dr. Liu, the world’s foremost expert on Jiaogulan, gave gypenosides (the active ingredient in Jiaogulan) to 610 healthy patients ages 50 to 90. They received the gypenosides for one month. Those patients between 70 and 90 years of age averaged a decrease in harmful oxidants of 21.4% and an average increase in the internally produced anti-oxidant SOD of 282.8%. Those patients in the age group 50 to 69 had a decrease in harmful oxidants averaging 15.6% and SOD increases of 116.1%. A control group did not experience any change thus suggesting the effects were due to the gypenosides.